A Network Flow-based Analysis of Cognitive Reserve in Normal Ageing and Alzheimer's Disease.
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ABSTRACT:
SUBMITTER: Wook Yoo S
PROVIDER: S-EPMC4438712 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
A Network Flow-based Analysis of Cognitive Reserve in Normal Ageing and Alzheimer's Disease.
Wook Yoo Sang S Han Cheol E CE Shin Joseph S JS Won Seo Sang S Na Duk L DL Kaiser Marcus M Jeong Yong Y Seong Joon-Kyung JK
Scientific reports 20150520
Cognitive reserve is the ability to sustain cognitive function even with a certain amount of brain damages. Here we investigate the neural compensation mechanism of cognitive reserve from the perspective of structural brain connectivity. Our goal was to show that normal people with high education levels (i.e., cognitive reserve) maintain abundant pathways connecting any two brain regions, providing better compensation or resilience after brain damage. Accordingly, patients with high education le ...[more]
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