Ontology highlight
ABSTRACT:
SUBMITTER: Frades I
PROVIDER: S-EPMC4439034 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Frades Itziar I Andreasson Erik E Mato Jose Maria JM Alexandersson Erik E Matthiesen Rune R Martínez-Chantar Maria Luz ML
PloS one 20150520 5
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for Hepatocellular carcinoma (HCC), but he transition from NAFLD to HCC is poorly understood. Feature selection algorithms in human and genetically modified mice NAFLD and HCC microarray data were applied to generate signatures of NAFLD progression and HCC differential survival. These signatures were used to study the pathogenesis of NAFLD derived HCC and explore which subtypes of cancers that can be investigated using mouse models. Our f ...[more]