Association of genetic polymorphisms in HTR3A and HTR3E with diarrhea predominant irritable bowel syndrome.
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ABSTRACT:
SUBMITTER: Gu QY
PROVIDER: S-EPMC4443222 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Association of genetic polymorphisms in HTR3A and HTR3E with diarrhea predominant irritable bowel syndrome.
Gu Qiao-Yan QY Zhang Jun J Feng Yi-Chao YC Dai Guang-Rong GR Du Wei-Ping WP
International journal of clinical and experimental medicine 20150315 3
<h4>Objective</h4>The present study aims to investigate the relationship between genetic polymorphisms in HTR3A and HTR3E and diarrhea predominant irritable bowel syndrome (D-IBS) in a Chinese population.<h4>Methods</h4>We enrolled 500 D-IBS patients and 500 age- and sex-matched healthy control subjects to detect the genotypes in HTR3A and HTR3B gene by using of PCR-RFLP method.<h4>Results</h4>There were significant difference between the D-IBS patients and the health control subjects in the dis ...[more]
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