Ontology highlight
ABSTRACT:
SUBMITTER: Zhang S
PROVIDER: S-EPMC4443227 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhang Shaoyan S Jiang Weihua W Tang Xiuming X Xu Quanchen Q Wang Jingli J Gui Rui R Zhang Xinhua X Liu Shiguo S
International journal of clinical and experimental medicine 20150315 3
<h4>Objective</h4>Multiple evidence suggests an involvement of the dopamine neurotransmitter system in Obsessive-compulsive disorder (OCD). Therefore, we explore the association of 3'UTR region of 40 bp variable tandem repeat (VNTR) polymorphism in Dopamine Transporter Gene (DAT1) in Chinese Han population.<h4>Methods</h4>A total of 305 OCD patients and 435 healthy individuals were recruited for the study. OCD was diagnosed with the Forth Edition (DSM-IV) diagnostic criteria. After polymerase ch ...[more]