Ontology highlight
ABSTRACT:
SUBMITTER: Schneider S
PROVIDER: S-EPMC4443624 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Immunity & ageing : I & A 20150520
<h4>Background</h4>Systolic blood pressure (SBP) increases steadily with age and bears an independent continuous relationship with the incidence of cardiovascular events. Low-grade inflammation is a suspected pathomechanism causing vascular aging and promote coronary artery disease (CAD). Recent animal studies give evidence that Toll-like receptor 4 (TLR4) modulate inflammation and contribute to age-dependent SBP increase. However, there are no data about TLR4 and age-dependent blood pressure in ...[more]