Tie me up, tie me down: inhibiting RNA polymerase.
Ontology highlight
ABSTRACT:
SUBMITTER: Sousa R
PROVIDER: S-EPMC4443808 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Publications
Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design. ...[more]
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