Secular trends in the incidence of primary hyperparathyroidism over five decades (1965-2010).

ABSTRACT: Introduction of automated serum calcium measurements in the 1970s resulted in a sharp rise in primary hyperparathyroidism (PHPT) incidence. However, recent investigations suggest a significant rise in PHPT incidence for unclear reasons. Our objective was to update our population-based secular trends in PHPT incidence, to determine if there has been a significant rise in PHPT incidence as suggested by others, and, if possible, to identify changes in clinical practice that might be responsible. Rochester, Minnesota, residents who met the criteria for PHPT from 2002 through 2010 were identified through the medical records-linkage system of the Rochester Epidemiology Project and added to the historical cohort beginning in 1965. Incidence rates were adjusted to the 2010 US white population. Alt

SUBMITTER: Griebeler ML 

PROVIDER: S-EPMC4445941 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature