Ontology highlight
ABSTRACT:
SUBMITTER: Emadpour M
PROVIDER: S-EPMC4446413 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Emadpour Masoumeh M Karcher Daniel D Bock Ralph R
Nucleic acids research 20150330 10
Riboswitches are RNA sensors that regulate gene expression in response to binding of small molecules. Although they conceptually represent simple on/off switches and, therefore, hold great promise for biotechnology and future synthetic biology applications, the induction of gene expression by natural riboswitches after ligand addition or removal is often only moderate and, consequently, the achievable expression levels are not very high. Here, we have designed an RNA amplification-based system t ...[more]