Ontology highlight
ABSTRACT:
SUBMITTER: Zhong J
PROVIDER: S-EPMC4446505 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhong Jixin J Gong Quan Q Goud Aditya A Srinivasamaharaj Srividya S Rajagopalan Sanjay S
Journal of diabetes research 20150514
DPP4 inhibitors (DPP4i) are a class of newly developed antidiabetic drugs which preserve incretin hormones and promote postprandial insulin secretion. Although the cardiovascular effect of DPP4 inhibition has been substantially studied, the exact role of DPP4 in cardiovascular disease especially in humans remains elusive. Previous small studies and meta-analyses have suggested a benefit in both surrogate outcomes and cardiovascular events for these agents. However, there was growing evidence in ...[more]