Ontology highlight
ABSTRACT:
SUBMITTER: Costas C
PROVIDER: S-EPMC4446724 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Costas Celina C López-Puente Vanesa V Bodelón Gustavo G González-Bello Concepción C Pérez-Juste Jorge J Pastoriza-Santos Isabel I Liz-Marzán Luis M LM
ACS nano 20150504 5
Many members of the LuxR family of quorum sensing (QS) transcriptional activators, including LasR of Pseudomonas aeruginosa, are believed to require appropriate acyl-homoserine lactone (acyl-HSL) ligands to fold into an active conformation. The failure to purify ligand-free LuxR homologues in nonaggregated form at the high concentrations required for their structural characterization has limited the understanding of the mechanisms by which QS receptors are activated. Surface-enhanced Raman scatt ...[more]