Recent advances in understanding and managing leiomyosarcomas.
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ABSTRACT:
SUBMITTER: Duffaud F
PROVIDER: S-EPMC4447031 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Recent advances in understanding and managing leiomyosarcomas.
Duffaud Florence F Ray-Coquard Isabelle I Salas Sébastien S Pautier Patricia P
F1000prime reports 20150512
Leiomyosarcomas are malignant mesenchymal tumours that derive from the smooth muscle lineage. They are studied and frequently treated as if they are the same as other soft tissue sarcomas. Recent developments suggest that a different approach may be more appropriate. Their underlying genetic mechanisms remain unclear, and complex. Unbalanced karyotypic defects are the only shared features observed across different leiomyosarcoma subtypes. Unlike other soft tissue sarcomas, leiomyosarcomas are pa ...[more]
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