Pathogenesis of Crohn's disease.
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ABSTRACT:
SUBMITTER: Boyapati R
PROVIDER: S-EPMC4447044 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Pathogenesis of Crohn's disease.
Boyapati Ray R Satsangi Jack J Ho Gwo-Tzer GT
F1000prime reports 20150402
Significant progress in our understanding of Crohn's disease (CD), an archetypal common, complex disease, has now been achieved. Our ability to interrogate the deep complexities of the biological processes involved in maintaining gut mucosal homeostasis is a major over-riding factor underpinning this rapid progress. Key studies now offer many novel and expansive insights into the interacting roles of genetic susceptibility, immune function, and the gut microbiota in CD. Here, we provide overview ...[more]
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