Ontology highlight
ABSTRACT:
SUBMITTER: Kim K
PROVIDER: S-EPMC4448937 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20091001 5955
Intraspecific chemical communication is mediated by signals called pheromones. Caenorhabditis elegans secretes a mixture of small molecules (collectively termed dauer pheromone) that regulates entry into the alternate dauer larval stage and also modulates adult behavior via as yet unknown receptors. Here, we identify two heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) that mediate dauer formation in response to a subset of dauer pheromone components. The SRBC-64 and SRBC ...[more]