Ontology highlight
ABSTRACT:
SUBMITTER: Groblewski PA
PROVIDER: S-EPMC4448949 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Groblewski Peter A PA Zietz Chad C Willuhn Ingo I Phillips Paul E M PE Chavkin Charles C
Addiction biology 20140215 2
Cocaine-experienced Wistar and Wistar Kyoto (WKY) rats received four daily repeated forced swim stress sessions (R-FSS), each of which preceded 4-hour cocaine self-administration sessions. Twenty-four hours after the last swim stress, cocaine valuation was assessed during a single-session threshold procedure. Prior exposure to R-FSS significantly altered cocaine responding in Wistar, but not WKY, rats. Behavioral economic analysis of responding revealed that the Wistar rats that had received R-F ...[more]