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The recent invasion of natural Drosophila simulans populations by the P-element.

ABSTRACT: The P-element is one of the best understood eukaryotic transposable elements. It invaded Drosophila melanogaster populations within a few decades but was thought to be absent from close relatives, including Drosophila simulans. Five decades after the spread in D. melanogaster, we provide evidence that the P-element has also invaded D. simulans. P-elements in D. simulans appear to have been acquired recently from D. melanogaster probably via a single horizontal transfer event. Expression data indicate that the P-element is processed in the germ line of D. simulans, and genomic data show an enrichment of P-element insertions in putative origins of replication, similar to that seen in D. melanogaster. This ongoing spread of the P-element in natural populations provides a unique opportunity to understand the dynamics of transposable element spread and the associated piwi-interacting RNAs defense mechanisms.

SUBMITTER: Kofler R

PROVIDER: S-EPMC4450375 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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The recent invasion of natural Drosophila simulans populations by the P-element.

Kofler Robert R Hill Tom T Nolte Viola V Betancourt Andrea J AJ Schlötterer Christian C

Proceedings of the National Academy of Sciences of the United States of America 20150511 21

The P-element is one of the best understood eukaryotic transposable elements. It invaded Drosophila melanogaster populations within a few decades but was thought to be absent from close relatives, including Drosophila simulans. Five decades after the spread in D. melanogaster, we provide evidence that the P-element has also invaded D. simulans. P-elements in D. simulans appear to have been acquired recently from D. melanogaster probably via a single horizontal transfer event. Expression data ind ...[more]

PMID: 25964349

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