Ontology highlight
ABSTRACT:
SUBMITTER: Datta J
PROVIDER: S-EPMC4451636 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Datta Jashodeep J Berk Erik E Cintolo Jessica A JA Xu Shuwen S Roses Robert E RE Czerniecki Brian J BJ
Frontiers in immunology 20150602
Dendritic cells (DC), master antigen-presenting cells that orchestrate interactions between the adaptive and innate immune arms, are increasingly utilized in cancer immunotherapy. Despite remarkable progress in our understanding of DC immunobiology, as well as several encouraging clinical applications - such as DC-based sipuleucel-T for metastatic castration-resistant prostate cancer - clinically effective DC-based immunotherapy as monotherapy for a majority of tumors remains a distant goal. The ...[more]