Oxidative Transformation of Controlled Substances by Manganese Dioxide.

ABSTRACT: This study investigated the oxidative transformation of four controlled substances (ketamine, methamphetamine, morphine, and codeine) by synthesized MnO2 (δ-MnO2) in aqueous environments. The results indicated that ketamine and methamphetamine were negligibly oxidized by MnO2 and, thus, may be persistent in the aqueous environment. However, morphine and codeine were able to be oxidized by MnO2, which indicated that they are likely naturally attenuated in aqueous environments. Overall, lower solution pH values, lower initial compound concentrations, and higher MnO2 loading resulted in a faster reaction rate. The oxidation of morphine was inhibited in the presence of metal ions (Mn(2+), Fe(3+), Ca(2+), and Mg(2+)) and fulvic acid. However, the addition of Fe(3+) and fulvic acid enhanced code

SUBMITTER: Lai WW 

PROVIDER: S-EPMC4452481 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature