Ontology highlight
ABSTRACT:
SUBMITTER: Arlt H
PROVIDER: S-EPMC4454181 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Arlt Henning H Auffarth Kathrin K Kurre Rainer R Lisse Dominik D Piehler Jacob J Ungermann Christian C
Molecular biology of the cell 20150205 7
Organelles of the endolysosomal system undergo multiple fission and fusion events to combine sorting of selected proteins to the vacuole with endosomal recycling. This sorting requires a consecutive remodeling of the organelle surface in the course of endosomal maturation. Here we dissect the remodeling and fusion machinery on endosomes during the process of endocytosis. We traced selected GFP-tagged endosomal proteins relative to exogenously added fluorescently labeled α-factor on its way from ...[more]