Pathway-based gene signatures predicting clinical outcome of lung adenocarcinoma.
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ABSTRACT:
SUBMITTER: Chang YH
PROVIDER: S-EPMC4455286 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Pathway-based gene signatures predicting clinical outcome of lung adenocarcinoma.
Chang Ya-Hsuan YH Chen Chung-Ming CM Chen Hsuan-Yu HY Yang Pan-Chyr PC
Scientific reports 20150604
Lung adenocarcinoma is often diagnosed at an advanced stage with poor prognosis. Patients with different clinical outcomes may have similar clinico-pathological characteristics. The results of previous studies for biomarkers for lung adenocarcinoma have generally been inconsistent and limited in clinical application. In this study, we used inverse-variance weighting to combine the hazard ratios for the four datasets and performed pathway analysis to identify prognosis-associated gene signatures. ...[more]
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