Ontology highlight
ABSTRACT:
SUBMITTER: Miao Y
PROVIDER: S-EPMC4458218 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Miao Yuxuan Y Li Guojie G Zhang Xiaoli X Xu Haoxing H Abraham Soman N SN
Cell 20150528 6
Vertebrate cells have evolved elaborate cell-autonomous defense programs to monitor subcellular compartments for infection and to evoke counter-responses. These programs are activated by pathogen-associated pattern molecules and by various strategies intracellular pathogens employ to alter cellular microenvironments. Here, we show that, when uropathogenic E. coli (UPEC) infect bladder epithelial cells (BECs), they are targeted by autophagy but avoid degradation because of their capacity to neutr ...[more]