Ontology highlight
ABSTRACT:
SUBMITTER: Khosa S
PROVIDER: S-EPMC4461328 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology communications 20150520 Pt 6
Nisin is a 34-amino-acid antimicrobial peptide produced by Lactococcus lactis belonging to the class of lantibiotics. Nisin displays a high bactericidal activity against various Gram-positive bacteria, including some human-pathogenic strains. However, there are some nisin-non-producing strains that are naturally resistant owing to the presence of the nsr gene within their genome. The encoded protein, NSR, cleaves off the last six amino acids of nisin, thereby reducing its bactericidal efficacy. ...[more]