Ontology highlight
ABSTRACT:
SUBMITTER: Hisada M
PROVIDER: S-EPMC4461878 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Hisada M M Ota Y Y Zhang X X Cameron A M AM Gao B B Montgomery R A RA Williams G M GM Sun Z Z
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120920 12
Livers from Lewis rats fed with 7% alcohol for 5 weeks were used for transplantation. Reduced sized (50%) livers or whole livers were transplanted into normal DA recipients, which, in this strain combination, survive indefinitely when the donor has not been fed alcohol. However, none of the rats survived a whole fatty liver transplant while six of seven recipients of reduced sized alcoholic liver grafts survived long term. SDF-1 and HGF were significantly increased in reduced size liver grafts c ...[more]