Ontology highlight
ABSTRACT:
SUBMITTER: Morales MM
PROVIDER: S-EPMC4461899 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Morales Marcelo M MM Souza Sérgio A L SA Loivos Luiz Paulo LP Lima Marina A MA Szklo Amir A Vairo Leandro L Brunswick Taís H K TH Gutfilen Bianca B Lopes-Pacheco Miquéias M Araújo Alberto J AJ Cardoso Alexandre P AP Goldenberg Regina C RC Rocco Patricia R M PR Fonseca Lea M B LM Lapa e Silva José R JR
BMC pulmonary medicine 20150611
<h4>Background</h4>Silicosis is an occupational disease for which no effective treatment is currently known. Systemic administration of bone marrow-derived mononuclear cells (BMDMCs) has shown to be safe in lung diseases. However, so far, no studies have analyzed whether bronchoscopic instillation of autologous BMDMCs is a safe route of administration in patients with silicosis.<h4>Methods</h4>We conducted a prospective, non-randomized, single-center longitudinal study in five patients. Inclusio ...[more]