Ontology highlight
ABSTRACT:
SUBMITTER: MacMillan ML
PROVIDER: S-EPMC4463740 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
MacMillan Margaret L ML DeFor Todd E TE Young Jo-Anne H JA Dusenbery Kathryn E KE Blazar Bruce R BR Slungaard Arne A Zierhut Heather H Weisdorf Daniel J DJ Wagner John E JE
Blood 20150330 24
Historically, alternative donor hematopoietic cell transplantation (HCT) for Fanconi anemia (FA) patients resulted in excessive morbidity and mortality. To improve outcomes, we made sequential changes to the HCT conditioning regimen. A total of 130 FA patients (median age, 9.0 years; range, 1-48) underwent alternative donor HCT at the University of Minnesota between 1995 and 2012. All patients received cyclophosphamide (CY), single fraction total body irradiation (TBI), and antithymocyte globuli ...[more]