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Hyperthermia Is Now Included in the NCCN Clinical Practice Guidelines for Breast Cancer Recurrences: An Analysis of Existing Data.


ABSTRACT:

Background

Hyperthermia has been included in the 2013 National Comprehensive Cancer Network (NCCN) guidelines as an option for the treatment of breast recurrences. The purpose of this article is to demonstrate the important role of hyperthermia as a therapeutic modality by presenting clinical trials on this subject carried out in the last decades.

Materials and methods

All relevant trials published since 1987 were retrieved from Medline and reviewed.

Results

Results show that the addition of hyperthermia to radiotherapy and/or chemotherapy for the treatment of breast cancer enhances treatment response and can increase local control.

Conclusion

Further studies are required to evaluate potential benefits of hyperthermia in the treatment of other kinds of superficial tumors.

SUBMITTER: Kouloulias V 

PROVIDER: S-EPMC4463790 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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Hyperthermia Is Now Included in the NCCN Clinical Practice Guidelines for Breast Cancer Recurrences: An Analysis of Existing Data.

Kouloulias Vassilis V   Triantopoulou Sotiria S   Uzunoglou Nikolaos N   Pistevou-Gompaki Kyriaki K   Barich Alfred A   Zygogianni Anna A   Kyrgias George G   Kardamakis Dimitris D   Pectasidis Dimitris D   Kouvaris John J  

Breast care (Basel, Switzerland) 20150401 2


<h4>Background</h4>Hyperthermia has been included in the 2013 National Comprehensive Cancer Network (NCCN) guidelines as an option for the treatment of breast recurrences. The purpose of this article is to demonstrate the important role of hyperthermia as a therapeutic modality by presenting clinical trials on this subject carried out in the last decades.<h4>Materials and methods</h4>All relevant trials published since 1987 were retrieved from Medline and reviewed.<h4>Results</h4>Results show th  ...[more]

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