Ontology highlight
ABSTRACT:
SUBMITTER: Lonnqvist S
PROVIDER: S-EPMC4464648 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Lönnqvist Susanna S Rakar Jonathan J Briheim Kristina K Kratz Gunnar G
PloS one 20150610 6
The possibility to use a suspended tridimensional matrix as scaffolding for re-epithelialization of in vitro cutaneous wounds was investigated with the aid of a human in vitro wound healing model based on viable full thickness skin. Macroporous gelatin microcarriers, CultiSpher-S, were applied to in vitro wounds and cultured for 21 days. Tissue sections showed incorporation of wound edge keratinocytes into the microcarriers and thicker neoepidermis in wounds treated with microcarriers. Thickness ...[more]