Ontology highlight
ABSTRACT:
SUBMITTER: Devaraj A
PROVIDER: S-EPMC4464964 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Devaraj Aishwarya A Justice Sheryl S SS Bakaletz Lauren O LO Goodman Steven D SD
Molecular microbiology 20150416 6
Most chronic and recurrent bacterial infections involve a biofilm component, the foundation of which is the extracellular polymeric substance (EPS). Extracellular DNA (eDNA) is a conserved and key component of the EPS of pathogenic biofilms. The DNABII protein family includes integration host factor (IHF) and histone-like protein (HU); both are present in the extracellular milieu. We have shown previously that the DNABII proteins are often found in association with eDNA and are critical for the ...[more]