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Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

ABSTRACT: The purpose of this study is to evaluate the long-term survival following gastric bypass using propensity-matched controls.We identified all patients who either received a gastric bypass (GBP) or met criteria to receive a GBP between January 1, 2002 and December 31, 2003. Propensity matching was performed. Long-term, all-cause mortality data were collected and evaluated using Kaplan-Meier curves.Four hundred thirty GBP cases and 5,323 controls were identified from the enrollment period. Ultimately, 802 cases and controls (1:1 matching, 93.2% match rate) were identified using propensity matching. Median follow-up was similar between groups. Overall mortality was lower for the GBP group (odds ratio .48, 95% confidence interval .29 to .78). GBP demonstrated significantly increased survival when compared with controls (P = .002). Similar patterns were noted among diabetics.We have demonstrated that gastric bypass provides a clear long-term survival advantage compared with nonsurgical propensity-matched controls.

SUBMITTER: Guidry CA

PROVIDER: S-EPMC4465556 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

Guidry Christopher A CA Davies Stephen W SW Sawyer Robert G RG Schirmer Bruce D BD Hallowell Peter T PT

American journal of surgery 20141223 3

<h4>Background</h4>The purpose of this study is to evaluate the long-term survival following gastric bypass using propensity-matched controls.<h4>Methods</h4>We identified all patients who either received a gastric bypass (GBP) or met criteria to receive a GBP between January 1, 2002 and December 31, 2003. Propensity matching was performed. Long-term, all-cause mortality data were collected and evaluated using Kaplan-Meier curves.<h4>Results</h4>Four hundred thirty GBP cases and 5,323 controls w ...[more]

PMID: 25601559

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Project description:BackgroundThere is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts.Materials and methodsThis analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien-Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups.ResultsIn total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07).ConclusionsThis global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts.

Dataset Information

Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

Publications

Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

Similar Datasets

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