Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC4465887 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Liu Haibin H Wang Lirong L Su Weiwei W Xie Xiang-Qun XQ
Pharmaceutical patent analyst 20140701 4
Alzheimer's disease (AD) is a progressive neurodegenerative disease, involving a large number of genes, proteins and their complex interactions. Currently, no effective therapeutic agents are available to either stop or reverse the progression of this disease, likely due to its polygenic nature. The complicated pathophysiology of AD remains unresolved. Although it has been hypothesized that the amyloid β cascade and the hyper-phosphorylated tau protein may be primarily involved, other mechanisms ...[more]