Ontology highlight
ABSTRACT:
SUBMITTER: Rimsza LM
PROVIDER: S-EPMC4467875 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Rimsza Lisa M LM Leblanc Michael L ML Unger Joseph M JM Miller Thomas P TP Grogan Thomas M TM Persky Daniel O DO Martel Ralph R RR Sabalos Constantine M CM Seligmann Bruce B Braziel Rita M RM Campo Elias E Rosenwald Andreas A Connors Joseph M JM Sehn Laurie H LH Johnson Nathalie N Gascoyne Randy D RD
Blood 20080610 8
Gene expression profiling (GEP) on frozen tissues has identified genes predicting outcome in patients with diffuse large B-cell lymphoma (DLBCL). Confirmation of results in current patients is limited by availability of frozen samples and addition of monoclonal antibodies to treatment regimens. We used a quantitative nuclease protection assay (qNPA) to analyze formalin-fixed, paraffin-embedded tissue blocks for 36 previously identified genes (N = 209, 93 chemotherapy; 116 rituximab + chemotherap ...[more]