Non-Coding RNAs in Primary Liver Cancer.
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ABSTRACT:
SUBMITTER: Ghidini M
PROVIDER: S-EPMC4469108 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Non-Coding RNAs in Primary Liver Cancer.
Ghidini Michele M Braconi Chiara C
Frontiers in medicine 20150604
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with poor prognosis and limited therapeutic options. Over the past few years, many studies have evaluated the role of non-coding RNAs (ncRNAs) in hepatocarcinogenesis and tumor progression. ncRNAs were shown to have diagnostic, prognostic, and therapeutic potential in HCC. In this manuscript, we review the latest major discoveries concerning microRNAs and long ncRNAs in HCC pathogenesis, and discuss the potentials and the limita ...[more]
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