Ontology highlight
ABSTRACT:
SUBMITTER: Yoon Y
PROVIDER: S-EPMC4469491 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Yoon Yeonsoo Y Huang Tingting T Tortelote Giovane G GG Wakamiya Maki M Hadjantonakis Anna-Katerina AK Behringer Richard R RR Rivera-Pérez Jaime A JA
Developmental biology 20150420 1
The establishment of the head to tail axis at early stages of development is a fundamental aspect of vertebrate embryogenesis. In mice, experimental embryology, genetics and expression studies have suggested that the visceral endoderm, an extra-embryonic tissue, plays an important role in anteroposterior axial development. Here we show that absence of Wnt3 in the posterior visceral endoderm leads to delayed formation of the primitive streak and that interplay between anterior and posterior visce ...[more]