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Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.

ABSTRACT: Choosing a diet rather than being prescribed one could improve weight loss.To examine whether offering choice of diet improves weight loss.Double-randomized preference trial of choice between 2 diets (choice) versus random assignment to a diet (comparator) over 48 weeks. (ClinicalTrials.gov: NCT01152359).Outpatient clinic at a Veterans Affairs medical center.Outpatients with a body mass index of at least 30 kg/m2.Choice participants received information about their food preferences and 2 diet options (low-carbohydrate diet [LCD] or low-fat diet [LFD]) before choosing and were allowed to switch diets at 12 weeks. Comparator participants were randomly assigned to 1 diet for 48 weeks. Both groups received group and telephone counseling for 48 weeks.The primary outcome was weight at 48 weeks.Of 105 choice participants, 61 (58%) chose the LCD and 44 (42%) chose the LFD; 5 (3 on the LCD and 2 on the LFD) switched diets at 12 weeks, and 87 (83%) completed measurements at 48 weeks. Of 102 comparator participants, 53 (52%) were randomly assigned to the LCD and 49 (48%) were assigned to the LFD; 88 (86%) completed measurements. At 48 weeks, estimated mean weight loss was 5.7 kg (95% CI, 4.3 to 7.0 kg) in the choice group and 6.7 kg (CI, 5.4 to 8.0 kg) in the comparator group (mean difference, -1.1 kg [CI, -2.9 to 0.8 kg]; P = 0.26). Secondary outcomes of dietary adherence, physical activity, and weight-related quality of life were similar between groups at 48 weeks.Only 2 diet options were provided. Results from this sample of older veterans might not be generalizable to other populations.Contrary to expectations, the opportunity to choose a diet did not improve weight loss.

SUBMITTER: Yancy WS

PROVIDER: S-EPMC4470323 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.

Yancy William S WS Mayer Stephanie B SB Coffman Cynthia J CJ Smith Valerie A VA Kolotkin Ronette L RL Geiselman Paula J PJ McVay Megan A MA Oddone Eugene Z EZ Voils Corrine I CI

Annals of internal medicine 20150601 12

<h4>Background</h4>Choosing a diet rather than being prescribed one could improve weight loss.<h4>Objective</h4>To examine whether offering choice of diet improves weight loss.<h4>Design</h4>Double-randomized preference trial of choice between 2 diets (choice) versus random assignment to a diet (comparator) over 48 weeks. (ClinicalTrials.gov: NCT01152359).<h4>Setting</h4>Outpatient clinic at a Veterans Affairs medical center.<h4>Patients</h4>Outpatients with a body mass index of at least 30 kg/m ...[more]

PMID: 26075751

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Project description:BACKGROUND:Some studies have shown that protein-enriched diets can lead to greater weight loss and improvements in biomarkers of metabolic syndrome (MeS) than standard protein diets. Therefore, the aim of this study was to determine the effect of increased protein intake on weight loss in Mexican adults with MeS. METHODS:Randomized controlled trial in 118 adults aged 47.4 ± 11.5 years and meeting the established criteria for MeS were randomized to prescribed hypocaloric diets (500 kcal less than resting metabolic rate) providing either 0.8 g/kg body weight (standard protein diet (SPD)) or 1.34 g/kg body weight (higher protein diet (HPD)) for 6 months. Body weight, waist circumference, percent body fat by bioimpedance analysis, fasting blood glucose, fasting insulin, hemoglobin A1c, total cholesterol, high-density lipoprotein (HDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, triglycerides, C-reactive protein, creatinine, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase were measured at baseline, 3 months and at 6 months. RESULTS:There were 105 subjects (51 for SPD and 54 for HPD) who completed the trial. Overall weight loss was 5.1 ± 3.6 kg in the SPD group compared to 7.0 ± 3.7 kg in the in HPD group. Both groups lost a significant percent of centimeters of waist circumference (SPD -6.5 ± 2.6 cm and HPD -8.8 ± 2.6 cm). There was no statistical difference Except for the varying weight losses the two groups did not show any further differences overall. However in the subgroup judged to be adherent more than 75% of the time with the prescribed diets, there was a significant difference in mean weight loss (SPD -5.8% vs. HPD -9.5%) after adjusting for baseline BMI. Both groups demonstrated significant decreases in waist circumference, glucose, insulin, triglycerides, and VLDL cholesterol, but there were no differences between the groups. There were no changes in blood tests for liver or renal function. CONCLUSIONS:There were no significant differences in weight loss and biomarkers of MeS when the overall group was examined, but the participants with more adherence rate in the HPD group lost significantly more weight than adherent participants in the SPD group.

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Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.

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Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.

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