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Deficient maternal zinc intake-but not folate-is associated with lower fetal heart rate variability.


ABSTRACT: Few studies of maternal prenatal diet and child development examine micronutrient status in relation to fetal assessment.Twenty-four-hour dietary recall of zinc and folate and 20min of fetal heart rate were collected from 3rd trimester pregnant adolescents.Deficient zinc was associated with less fetal heart rate variability. Deficient folate had no associations with HRV. Neither deficient zinc nor deficient folate was related to fetal heart rate.These findings, from naturalistic observation, are consistent with emerging data on prenatal zinc supplementation using a randomized control design.Taken together, the findings suggest that maternal prenatal zinc intake is an important and novel factor for understanding child ANS development.

SUBMITTER: Spann MN 

PROVIDER: S-EPMC4471999 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Deficient maternal zinc intake-but not folate-is associated with lower fetal heart rate variability.

Spann Marisa N MN   Smerling Jennifer J   Gustafsson Hanna H   Foss Sophie S   Altemus Margaret M   Monk Catherine C  

Early human development 20150203 3


<h4>Objective</h4>Few studies of maternal prenatal diet and child development examine micronutrient status in relation to fetal assessment.<h4>Methods</h4>Twenty-four-hour dietary recall of zinc and folate and 20min of fetal heart rate were collected from 3rd trimester pregnant adolescents.<h4>Results</h4>Deficient zinc was associated with less fetal heart rate variability. Deficient folate had no associations with HRV. Neither deficient zinc nor deficient folate was related to fetal heart rate.  ...[more]

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