Ontology highlight
ABSTRACT:
SUBMITTER: Zhang F
PROVIDER: S-EPMC4472075 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhang Feng F Liu Xiaowei X Wang Bailing B Cheng Zaohuo Z Zhao Xingfu X Zhu Jianzhong J Wang Degang D Wang Ying Y Dong Aiguo A Li Pengpeng P Jin Chunhui C
Neuropsychiatric disease and treatment 20150612
In previous studies, we reported that the sortilin-related receptor, L (DLR class) A repeats containing (SORL1) gene single nucleotide polymorphisms (SNPs) are associated with the risk of sporadic Alzheimer's disease (SAD) in the Han Chinese population. To further explore the relationships between SORL1 genetic variants and SAD, we conducted a two-step study. Sequencing analysis in 50 case samples identified 14 SNPs within the promoter and untranslated region of the SORL1 gene. Subsequent genoty ...[more]