Ontology highlight
ABSTRACT:
SUBMITTER: Kratchmarov R
PROVIDER: S-EPMC4474295 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Kratchmarov R R Enquist L W LW Taylor M P MP
Journal of virology 20150401 12
Axonal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the viral protein Us9. Here we identify a Us9-independent mechanism for axonal localization of viral glycoprotein M (gM). We detected gM-mCherry assemblies transporting in the anterograde direction in axons. Furthermore, unlabeled gM, but not glycoprotein B, was detected by Western blotting in isolated axons during Us9-null PRV infection. These results suggest that gM differs from other viral protein ...[more]