Ontology highlight
ABSTRACT:
SUBMITTER: Hwang W
PROVIDER: S-EPMC4474542 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Hwang Woochang W Oliver Verity F VF Merbs Shannath L SL Zhu Heng H Qian Jiang J
BMC genomics 20150611
<h4>Background</h4>Regulatory regions (e.g. promoters and enhancers) play an essential role in human development and disease. Many computational approaches have been developed to predict the regulatory regions using various genomic features such as sequence motifs and evolutionary conservation. However, these DNA sequence-based approaches do not reflect the tissue-specific nature of the regulatory regions. In this work, we propose to predict regulatory regions using multiple features derived fro ...[more]