Ontology highlight
ABSTRACT:
SUBMITTER: Pappas D
PROVIDER: S-EPMC4476503 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Human immunology 20150207 2-3
Multiple lines of evidence support an immunologic basis and genetic disposition for the development of age-related macular degeneration (AMD). Comprehensive human leukocyte antigens (HLA) class II typing at four loci (DRB1, DQA1, DQB1, and DPB1) was assessed using next generation sequencing methods and tested for association with age-related macular degeneration (AMD) in a case-control study of 456 AMD cases and 499 controls from the population-based Study of Osteoporotic Fractures (SOF) cohort. ...[more]