Ontology highlight
ABSTRACT:
SUBMITTER: Prudente S
PROVIDER: S-EPMC4477355 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Prudente Sabrina S Shah Hetal H Bailetti Diego D Pezzolesi Marcus M Buranasupkajorn Patinut P Mercuri Luana L Mendonca Christine C De Cosmo Salvatore S Niewczas Monika M Trischitta Vincenzo V Doria Alessandro A
Diabetes 20150212 7
Single nucleotide polymorphism (SNP) rs10911021 at the glutamate-ammonia ligase (GLUL) locus has been associated with an increased risk of coronary heart disease in individuals with type 2 diabetes. The effect of this SNP on mortality was investigated among 1,242 white subjects with type 2 diabetes from the Joslin Kidney Study (JKS) (n = 416) and the Gargano Mortality Study (GMS) (n = 826). During a mean follow-up of 12.8 ± 5.8 and 7.5 ± 2.2 years, respectively, a total of 215 and 164 deaths wer ...[more]