Ontology highlight
ABSTRACT:
SUBMITTER: Payen DM
PROVIDER: S-EPMC4477725 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Payen Didier M DM Guilhot Joelle J Launey Yoann Y Lukaszewicz Anne Claire AC Kaaki Mahmoud M Veber Benoit B Pottecher Julien J Joannes-Boyau Olivier O Martin-Lefevre Laurent L Jabaudon Matthieu M Mimoz Olivier O Coudroy Rémi R Ferrandière Martine M Kipnis Eric E Vela Carlos C Chevallier Stéphanie S Mallat Jihad J Robert René R
Intensive care medicine 20150411 6
<h4>Purpose</h4>To test whether the polymyxin B hemoperfusion (PMX HP) fiber column reduces mortality and organ failure in peritonitis-induced septic shock (SS) from abdominal infections.<h4>Method</h4>Prospective, multicenter, randomized controlled trial in 18 French intensive care units from October 2010 to March 2013, enrolling 243 patients with SS within 12 h after emergency surgery for peritonitis related to organ perforation. The PMX HP group received conventional therapy plus two sessions ...[more]