SecA: a potential antimicrobial target.
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ABSTRACT:
SUBMITTER: Chaudhary AS
PROVIDER: S-EPMC4479503 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
SecA: a potential antimicrobial target.
Chaudhary Arpana S AS Chen Weixuan W Jin Jinshan J Tai Phang C PC Wang Binghe B
Future medicinal chemistry 20150101 8
There is a consensus in the medical profession of the pressing need for novel antimicrobial agents due to issues related to drug resistance. In practice, solutions to this problem to a large degree lie with the identification of new and vital targets in bacteria and subsequently designing their inhibitors. We consider SecA a very promising antimicrobial target. In this review, we compile and analyze information available on SecA to show that inhibition of SecA has a multitude of consequences. Fu ...[more]
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