Ontology highlight
ABSTRACT:
SUBMITTER: Park SH
PROVIDER: S-EPMC4480226 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Park Su-Hyung SH Rehermann Barbara B
Immunity 20140101 1
Five human hepatitis viruses cause most of the acute and chronic liver disease worldwide. Over the past 25 years, hepatitis C virus (HCV) in particular has received much interest because of its ability to persist in most immunocompetent adults and because of the lack of a protective vaccine. Here we examine innate and adaptive immune responses to HCV infection. Although HCV activates an innate immune response, it employs an elaborate set of mechanisms to evade interferon (IFN)-based antiviral im ...[more]