Ontology highlight
ABSTRACT:
SUBMITTER: Patil PC
PROVIDER: S-EPMC4480780 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Tetrahedron letters 20150601 23
New routes to 2, 4, 5-trisubstituted oxazoles were established whereby the substitution pattern was established by the structure of the starting nonsymmetrical acyloins. 2-Chloromethyl-4, 5-disubstituted oxazoles were prepared by refinements of an earlier described process whereby chloroacetyl esters of symmetrical and non-symmetrical acyloins were cyclized using an ammonium acetate/acetic acid protocol. After substitution is effected, the azide moiety is then installed by substitution under mil ...[more]