Ontology highlight
ABSTRACT:
SUBMITTER: Macosko EZ
PROVIDER: S-EPMC4481139 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Cell 20150501 5
Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of ease and scale have prevented its broad application. Here we describe Drop-seq, a strategy for quickly profiling thousands of individual cells by separating them into nanoliter-sized aqueous droplets, associating a different barcode with each cell's RNAs, and sequencing them all together. Drop-seq analyzes mRNA transcrip ...[more]