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Mitochondrial donation--how many women could benefit?

ABSTRACT: Mitochondrial disease is maternally inherited and refractory to treatment, but assisted reproduction methods can result in unaffected pregnancies. The authors provide estimates of the number of affected pregnancies per year in the United Kingdom and the United States.

SUBMITTER: Gorman GS 

PROVIDER: S-EPMC4481295 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Mitochondrial donation--how many women could benefit?

Gorman Gráinne S GS   Grady John P JP   Turnbull Doug M DM  

The New England journal of medicine 20150128 9

Mitochondrial disease is maternally inherited and refractory to treatment, but assisted reproduction methods can result in unaffected pregnancies. The authors provide estimates of the number of affected pregnancies per year in the United Kingdom and the United States. ...[more]

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