Ontology highlight
ABSTRACT:
SUBMITTER: Beale MA
PROVIDER: S-EPMC4482434 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
PLoS neglected tropical diseases 20150625 6
Cryptococcal meningitis is a major cause of mortality throughout the developing world, yet little is known about the genetic markers underlying Cryptococcal virulence and patient outcome. We studied a cohort of 230 Cryptococcus neoformans (Cn) isolates from HIV-positive South African clinical trial patients with detailed clinical follow-up using multi-locus sequence typing and in vitro phenotypic virulence assays, correlating these data with clinical and fungal markers of disease in the patient. ...[more]