Ontology highlight
ABSTRACT:
SUBMITTER: Rutishauser U
PROVIDER: S-EPMC4482779 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Rutishauser Ueli U Ye Shengxuan S Koroma Matthieu M Tudusciuc Oana O Ross Ian B IB Chung Jeffrey M JM Mamelak Adam N AN
Nature neuroscience 20150608 7
Memory-based decisions are often accompanied by an assessment of choice certainty, but the mechanisms of such confidence judgments remain unknown. We studied the response of 1,065 individual neurons in the human hippocampus and amygdala while neurosurgical patients made memory retrieval decisions together with a confidence judgment. Combining behavioral, neuronal and computational analysis, we identified a population of memory-selective (MS) neurons whose activity signaled stimulus familiarity a ...[more]