Ontology highlight
ABSTRACT:
SUBMITTER: Comoy EE
PROVIDER: S-EPMC4485159 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20150630
Classical bovine spongiform encephalopathy (c-BSE) is the only animal prion disease reputed to be zoonotic, causing variant Creutzfeldt-Jakob disease (vCJD) in humans and having guided protective measures for animal and human health against animal prion diseases. Recently, partial transmissions to humanized mice showed that the zoonotic potential of scrapie might be similar to c-BSE. We here report the direct transmission of a natural classical scrapie isolate to cynomolgus macaque, a highly rel ...[more]