Ontology highlight
ABSTRACT:
SUBMITTER: Ridder K
PROVIDER: S-EPMC4485784 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Ridder Kirsten K Sevko Alexandra A Heide Janina J Dams Maria M Rupp Anne-Kathleen AK Macas Jadranka J Starmann Julia J Tjwa Marc M Plate Karl H KH Sültmann Holger H Altevogt Peter P Umansky Viktor V Momma Stefan S
Oncoimmunology 20150319 6
Extracellular vesicles (EVs) have been shown to transfer various molecules, including functional RNA between cells and this process has been suggested to be particularly relevant in tumor-host interactions. However, data on EV-mediated RNA transfer has been obtained primarily by <i>in vitro</i> experiments or involving <i>ex vivo</i> manipulations likely affecting its biology, leaving their physiological relevance unclear. We engineered glioma and carcinoma tumor cells to express Cre recombinase ...[more]