Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC4486725 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhang Limeng L Zhang Hua H Fan Ziyao Z Zhou Xue X Yu Liquan L Sun Hunan H Wu Zhijun Z Yu Yongzhong Y Song Baifen B Ma Jinzhu J Tong Chunyu C Wang Xintong X Zhu Zhanbo Z Cui Yudong Y
PloS one 20150629 6
The GapC of Streptococcus dysgalactiae (S. dysgalactiae) is a highly conserved surface protein that can induce protective humoral immune response in animals. However, B-cell epitopes on the S. dysgalactiae GapC have not been well identified. In this study, a monoclonal antibody (mAb5B7) against the GapC1-150 protein was prepared. After passive transfer, mAb5B7 could partially protect mice against S. dysgalactiae infection. Eleven positive phage clones recognized by mAb5B7 were identified by scre ...[more]